KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AOPEP
All Species:
18.18
Human Site:
T224
Identified Species:
44.44
UniProt:
Q8N6M6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N6M6
NP_116212.3
819
93572
T224
E
L
L
F
D
T
D
T
W
S
L
Q
I
R
K
Chimpanzee
Pan troglodytes
XP_001150193
819
93483
T224
E
L
L
F
D
T
D
T
W
S
L
Q
I
R
K
Rhesus Macaque
Macaca mulatta
XP_001105417
819
92641
T224
E
L
L
F
D
T
D
T
W
S
L
Q
I
R
K
Dog
Lupus familis
XP_848283
819
93374
T224
E
L
L
F
D
T
D
T
W
S
L
Q
I
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXQ6
817
92937
N224
E
L
L
I
D
S
D
N
W
S
L
R
I
R
K
Rat
Rattus norvegicus
P69527
816
92818
K224
E
L
L
F
D
S
D
K
W
S
L
Q
I
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231898
826
93758
S226
E
L
E
F
T
T
G
S
W
S
L
E
I
R
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001116730
787
89175
D208
K
G
V
R
T
P
H
D
F
P
C
A
V
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193484
790
88543
E237
Q
A
I
I
H
A
P
E
E
I
M
V
V
M
S
Poplar Tree
Populus trichocarpa
XP_002316336
620
70279
S99
S
S
V
L
I
L
Y
S
T
S
P
S
S
S
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
92.8
84.3
N.A.
76.4
77
N.A.
N.A.
71.6
N.A.
54.4
N.A.
N.A.
N.A.
N.A.
37.8
Protein Similarity:
100
99.1
95.8
90.5
N.A.
84.9
84.9
N.A.
N.A.
84
N.A.
67.2
N.A.
N.A.
N.A.
N.A.
56.4
P-Site Identity:
100
100
100
100
N.A.
73.3
86.6
N.A.
N.A.
66.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
N.A.
80
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
21.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
38.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
0
0
0
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
60
0
60
10
0
0
0
0
0
0
0
% D
% Glu:
70
0
10
0
0
0
0
10
10
0
0
10
0
0
0
% E
% Phe:
0
0
0
60
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
20
10
0
0
0
0
10
0
0
70
0
10
% I
% Lys:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
70
% K
% Leu:
0
70
60
10
0
10
0
0
0
0
70
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
10
0
0
10
10
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
10
0
80
0
% R
% Ser:
10
10
0
0
0
20
0
20
0
80
0
10
10
10
10
% S
% Thr:
0
0
0
0
20
50
0
40
10
0
0
0
0
0
0
% T
% Val:
0
0
20
0
0
0
0
0
0
0
0
10
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _